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Advisors

Neuroscience Advisors

The following faculty, organized by department with their most recent publications listed, serve as advisors to the Neuroscience major--click on person's name to send an email. 

PSYCHOLOGY


Lori DriscollLori Driscoll

Neurotoxicology: effects of prenatal and/or early postnatal exposure to environmental pollutants or other neurotoxins on cognitive and affective processes; Nutritional supplementation as a means to prevent or lessen neurotoxin-induced cognitive dysfunction; Psychopharmacology of higher cognitive functions.

Selected publications

Bushnell, P. J. & Driscoll, L. L. (2015). Cognitive function. In M. Caplan, Reference Module in Biomedical Research. Elsevier, Inc. doi: 10.1016/B978-0-12-801238-3.02206-6  pdf

Driscoll, L. L., Kaplan, J., Bucuvalas, E., Allen, H., Kraut, J., & Fitzpatrick, J. (2012). Acute postnatal exposure to the pentaBDE commercial mixture DE-71 at doses of 5 or 15 mg/kg/day does not produce learning or attention deficits in rats. Neurotoxicology and Teratology, 34, 20-26. pdf

Driscoll, L. L., Gibson, A. M., & Hieb, A. (2009). Chronic postnatal DE-71 exposure: Effects on learning, attention and thyroxine levels. Neurotoxicology and Teratology, 31, 76-84. pdf

Moon, J., Ota, K. T., Driscoll, L. L., Levitsky, D. A., & Strupp, B. J. (2008). A mouse model of Fragile X syndrome exhibits heightened arousal and/or emotion following errors or reversal of contingencies. Developmental Psychobiology, 50, 473-485. pdf

Moon, J., Beaudin, A. E., Verosky, S., Driscoll, L. L., Weiskopf, M., Levitsky, D. A., Crnic, L. S., & Strupp, B. J. (2006). Attentional dysfunction, impulsivity, and resistance to change in a mouse model of Fragile X Syndrome. Behavioral Neuroscience, 120, 1367-1379. pdf

Dufault, C., Poles, G., & Driscoll, L. L. (2005). Brief postnatal PBDE exposure alters learning and the cholinergic modulation of attention in rats. Toxicological Sciences, 88, 172-180. pdf

Driscoll, L. L., Carroll, J. C., Moon, J., Crnic, L. S., Levitsky, D. A., & Strupp, B. J. (2004). Impaired sustained attention and error-induced stereotypy in the aged Ts65Dn mouse, a mouse model of Down syndrome and Alzheimer disease. Behavioral Neuroscience, 118, 1196-1205. pdf

Morgan, R.E., Garavan, H., Smith, E.G., Driscoll, L.L., Levitsky, D.A., & Strupp, B.J. (2001). Early lead exposure produces lasting changes in sustained attention, response initiation, and reactivity to errors. Neurotoxicology and Teratology, 23, 519-531.


Kristi ErdalKristi Erdal

Depression and anxiety in Parkinson’s disease and other neurological disorders, malingering of neuropsychological impairment, sport psychology.

Selected publications

Riciputi, S. and Erdal, K. (2017). The effect of stereotype threat on student-athlete math performance. Psychology of Sport and Exercise, 32, 54-57.

Kelly, K. and Erdal, K. (2016). Diagnostic terminology, athlete status, and history of concussion affect return to play expectations and anticipated symptoms following mild traumatic brain injury.  Journal of Clinical and Experimental Neuropsychology, 39(6), 587-595. 

Pfeffer, C. and Erdal, K. (2015). Perceptions of former child soldiers and LRA victims with post-traumatic stress among health professionals and lay people in Northern Uganda.  International Perspectives in Psychology:  Research, Practice, Consultation, 4(2), 128-141.

Draganich, C. and Erdal, K. (2014). Placebo sleep affects cognitive functioning. Journal of Experimental Psychology:  Learning, Memory and Cognition, 40(3), 857-864.

Erdal, K. (2012). Neuropsychological testing for sports-related concussion:  How athletes can sandbag their baseline testing without detection.  Archives of Clinical Neuropsychology, 27(5), 473-479

Erdal, K., Singh, N., & Tardif, A. (2011). Attitudes about depression and its treatment among mental health professionals, lay persons and immigrants and refugees in Norway. Journal of Affective Disorders, 133, 481-488.doi:10.1016/j.jad.2011.04.038

Erdal, K. (2009). Why one fakes a head injury affects how one fakes a head injury. Applied Neuropsychology, 16, 42-48.

Erdal, K. (2004). The effects of motivation, coaching, and knowledge of neuropsychology on the simulated malingering of head injury. Archives of Clinical Neuropsychology, 19(1), 73-88.

Erdal, K. (2001). Depressive symptom patterns in patients with Parkinson's disease and other older adults. Journal of Clinical Psychology, 57, 1559-1569.

Erdal, K. (2001). Depression and anxiety in Parkinson’s disease patients with and without “on-off” phenomena. Journal of Clinical Psychology in Medical Settings, 8, 293-299.

Johnstone, B. and Erdal, K. (1995). The relationship between the WMS-R Attention Index and putative measures of attention. Journal of Clinical Psychology in Medical Settings, 2, 195-204.

Youngjohn, J., Burrows, L., & Erdal, K. (1995). Brain damage or compensation neurosis?  The controversial post-concussion syndrome. The Clinical Neuropsychologist, 9, 112-123.

 


John HornerJohn Horner

Animal Learning and Adaptation; Neural Networks; Human Memory; Meaning and Categorization.

Selected publications

Horner, J. M., & Tung, S. K.  (2011).  Playing cards with Thomas Kuhn: A critical reexamination of the Bruner and Postman (1949) experiment.  Review of General Psychology, 15, 175-185.

Horner, J. M. (2008). The end of psychology: What can we expect at the limits of inquiry? In N. K. Innis (Ed.) Reflections on Adaptive Behavior: Essays in Honor of J. E. R. Staddon. Cambridge: MIT Press.

Horner, J. M., & Comstock, S. P. (2005). What are the important visual features for coin discrimination? Applied Cognitive Psychology, 19,1211-1218.

Horner, J. M. (2002) Information in the behavior stream. Behavioural Processes, 58, 133-147.

Horner, J. M., Staddon, J. E. R. & Lozano, K. K. (1997). Integration of reinforcement effects over time. Animal Learning & Behavior, 25, 84-98.

Horner, J. M. (1996). If the eye were an animal… The problem of representation in understanding, meaning and intelligence. Journal of Consciousness Studies, 3, 127-38.

 


Bob JacobsBob Jacobs

Neuroscience; Comparative Neuroanatomy; Cognitive Neuroethology; Language Acquisition; Non-Human Animal Communication;  Evolutionary Neurobiology; Neuromorphology. 

Selected publications

Jacobs, B., Garcia, M.E., Shea-Shumsky, N.B., Tennison, M.E., Schall, M., Saviano, M.S., Tummino, T. A., Bull, A.J., Driscoll, L.L., Raghanti, M.A., Lewandowski, A.H., Wicinski, B., Chui, H.K., Bertelsen, M.F. Walsh, T., Bhagwandin, A., Spocter, M.A., Hof, P.R., Sherwood, C.C., & Manger, P.R.  (2018).  Comparative morphology of gigantopyramidal neurons in primary motor cortex across mammals.  Journal of Comparative Neurology, 526, 496-536.  doi: 10.1002/cne.24349 pdf

Jacobs, B.  (2017).  Arnold Bernard Scheibel, M.D. (1923-2017).  Journal of Comparative Neurology, 525, 2459-2464.  doi: 10.1002/cne.24231  pdf

Johnson, C.B., Schall, M., Tennison, M.E., Garcia, M.E., Shea-Shumsky, N.B., Raghanti, M.A., Lewandowski, A., Bertelsen, M.F., Waller, L.C., Walsh, T., Roberts, J.F., Hof, P.R., Sherwood, C.C., Manger, P.R., & Jacobs, B. (2016). Neocortical neuronal morphology in the Siberian tiger (Panthera tigris altaica) and the clouded leopard (Neofelis nebulosa). Journal of Comparative Neurology.  doi: 10.1002/cne.24022  pdf

Reyes, L.D., Harland, T., Reep, R.L., Jacobs, B., & Sherwood, C.C. (2016). Golgi analysis of neuron morphology in the presumptive somatosensory cortex and visual cortex of the Florida manatee (Trichechus manatus latirostris). Brain, Behavior, and Evolution, 87, 105-116. doi: 10.1159/000445495  pdf

Jacobs, B., Lee, L., Schall, M., Raghanti, M.A., Lewandowski, A., Kottwitz, J.J., Roberts, J.F., Hof, P.R., & Sherwood, C.C. (2015). Neocortical neuronal morphology in the newborn giraffe (Giraffa camelopardalis tipelskirchi) and African elephant (Loxodonta africana). Journal of Comparative Neurology.    doi: 10.1002/cne.23841  pdf

Butti, C., Janeway, C.M., Townshend, C., Ridgway, S.H., Sherwood, C.C., Hof, P.R., & Jacobs, B. (2014).  The neocortex of cetartiodactyls. I.  A comparative Golgi analysis of neuronal morphology in the bottlenose dolphin (Tursiops truncatus), the minke whale (Balaenoptera acutorostrata), and the humpback whale (Megaptera novaeangliae). Brain Structure and Function, 220, 3339-3368. doi:  10.1007/s00429-014-0860-3  pdf

Jacobs, B., Harland, T., Kennedy, D., Schall, M., Wicinski, B., Butti, C., Hof, P.R., Sherwood, C.C., & Manger, P.R. (2014).  The neocortex of cetartiodactyls. II.  Neuronal morphology of the visual and motor cortices in the giraffe (Giraffa camelopardalis).  Brain Structure and Function, 220, 2851-2872. doi: 10.1007/s00429-014-0830-9  pdf

Jacobs, B., Johnson, N., Wahl, D., Schall, M., Maseko, B.C., Lewandowski, A., Raghanti, M.A., Wicinski, B., Butti, C., Hipkins, W. D., Bertelsen, M.F., Reep, R. L., Hof, P.R., Sherwood, C.C., & Manger, P.R. (2014).  Comparative neuronal morphology of cerebellar cortex in afrotherians (African elephant, Florida manatee), primates (human, common chimpanzee), cetartiodactyls (humpback whale, giraffe), and carnivores (Siberian tiger, clouded leopard).  Frontiers Neuroanatomy, 8:24. doi: 10.3389/fnana.2014.00024  pdf

Bianchi, S. Stimpson, C.D., Duka, T., Larsen, M.D., Janssen, W.G., Collins, Z., Bauernfeind, A.L., Schapiro, S.J., Baze, W.B., McArthur, M.J., Hopkins W.D., Wildman, D.E., Lipovich, L., Kuzawa, C.W., Jacobs, B., Hof, P.R. & Sherwood, C.C. (2013). Synaptogenesis and development of pyramidal neuron dendritic morphology in the chimpanzee neocortex. Proceedings of the National Academy of Sciences, 110, 10395-10401. doi: 10.1073/pnas.1301224110  pdf

Jacobs, B., Lubs, J., Hannan, M., Anderson, K., Butti, C., Sherwood, C.C., Hof, P.R., & Manger, P.R. (2011). Neuronal morphology in the African elephant (Loxodonta africana) neocortex. Brain Structure and Function, 215, 273-298. doi: 10.1007/s00429-010-0288-3. pdf  Science announcement   Overview in The Conversation

Anderson, K., Yamamoto, E., Kaplan, J., Hannan, M., & Jacobs, B. (2010). Neurolucida lucivid versus Neurolucida camera: A quantitative and qualitative comparison of three-dimensional neuronal reconstructions. Journal of Neuroscience Methods, 186, 209-214. doi:10.1016/ j.jneumeth.2009.11.024. pdf

Anderson, K., Bones, B., Robinson, B., Hass, C. Lee, H., Ford, K., Roberts T-A., & Jacobs, B . (2009). The morphology of supragranular pyramidal neurons in the human insular cortex: A quantitative Golgi study. Cerebral Cortex, 19 ,2131-2144. doi: 10.1093/cercor/bhn234. pdf

Travis, K., Ford, K., & Jacobs, B. (2005). Regional dendritic variation in neonatal human cortex: A quantitative Golgi study. Developmental Neuroscience, 27, 277-287. pdf

Jacobs, B., & Scheibel, A.B. (2002). Regional dendritic variation in primate cortical pyramidal cells. In A. Schüz & R. Miller, Cortical areas: Unity and diversity (Conceptual advances in brain research series; pp. 111-131). London: Taylor & Francis.  pdf

Jacobs, B., Schall, M., Prather, M., Kapler, L., Driscoll, L., Baca, S., Jacobs, J., Ford, K., Wainwright, M. & Treml, M. (2001). Regional dendritic and spine variation in human cerebral cortex: A quantitative Golgi study. Cerebral Cortex, 11, 558-571. pdf

 


MOLECULAR BIOLOGY

Darrell Killian

Darryl

Dendrite morphogenesis in C. elegans, cell cycle and sex determination; more information here.

Selected publications

(Note:  # mentored undergraduate students, * primary authors with equal contribution, ^ co-corresponding authors)

Olesnicky EC, Antonacci S, Popitsch N, Lybecker MC, Titus MB, Valadez R, Derkach PG, Marean A, Miller K#, Mathai SK#, Killian DJ (2018). Shep interacts with posttranscriptional regulators to control dendrite morphogenesis in sensory neurons. Developmental Biology 444, 116-128.

Schachtner LT, Sola IE, Forand D, Antonacci S, Postovit AJ, Mortimer NT, Killian DJ^, Olesnicky EC^ (2015) Drosophila Shep and C. elegans SUP-26 are RNA-binding proteins that play diverse roles in nervous system development. Development, Genes, and Evolution 225, 319-330.

Antonacci S, Forand D, Wolf M#, Tyus C#, Barney J#, Kellogg L#, Simon MA#, Kerr G#, Wells KL#, Younes S, Mortimer NT, Olesnicky EC^, Killian DJ^ (2015). Conserved RNA-Binding Proteins Required for Dendrite Morphogenesis in Caenorhabditis elegans Sensory Neurons. G3: Genes, Genomes, Genetics 5:2, 639-653.

Wells KL#, Rowneki M#, Killian DJ (2015). A splice acceptor mutation in C. elegans daf-19/Rfx disrupts functional specialization of male-specific ciliated neurons but does not affect ciliogenesis. Gene 559, 196-202.

Olesnicky EC, Killian DJ, Rathjen AR, Garcia E, Sola IE, Gavis ER (2014). Extensive use of RNA binding proteins in dendrite morphogenesis of Drosophila sensory neurons. G3: Genes, Genomes, Genetics 4.

Killian DJ, Harvey E#, Johnson P#, Otori M, Mitani S, Xue D (2008). SKR-1, a homolog of Skp1 and a member of the SCFSEL-10 complex, regulates sex-determination and LIN-12/Notch signaling in C. elegans.  Developmental Biology 322, 322-331.

Peden E, Killian DJ, Xue D (2008). Cell death specification in C. elegans.  Cell Cycle 7, 2479-2484.

Voutev R*, Killian DJ*, Ahn JH, Hubbard EJ (2006).  Alterations in ribosome biogenesis cause specific defects in C. elegans hermaphrodite gonadogenesis.  Developmental Biology 298, 45-58.

Killian DJ and Hubbard EJA (2005). Caenorhabditis elegans germline patterning requires coordinated development of the somatic gonadal sheath and the germline.  Developmental Biology 279, 322-335.

Maciejowski J#, Ahn J, Cipriani PG, Killian DJ, Chaudhary AL#, Lee, JI, Voutev R, Johnsen, RC, Baillie, DL, Gunsalus KC, Fitch DHA, Hubbard EJA (2005). Autosomal genes of autosomal/X-linked duplicated gene pairs and germline proliferation in C. elegansGenetics 169, 1997-2011.

Killian DJ and Hubbard EJA (2004). C. elegans pro-1 is required for soma/germline interactions that influence proliferation and differentiation in the germ line.  Development 131, 1267-1278.

Pepper A S-R, Lo T-W, Killian DJ, Hall DH, Hubbard EJA (2003). The establishment of Caenorhabditis elegans germline pattern is controlled by overlapping proximal and distal somatic gonad signals. Developmental Biology 259, 336-350.

Pepper A S-R, Killian DJ, Hubbard EJA (2003). Genetic Analysis of Caenorhabditis elegans glp-1 Mutants Suggests Receptor Interaction or Competition. Genetics 163, 115-132.

Schaeffer V, Killian D, Desplan C, Wimmer E (2000). High bicoid levels render the terminal system dispensable for Drosophila head development. Development 127, 3993-3999.

Mollereau B, Wernet M, Beaufils P, Killian D, Pichaud F, Kuhnlein R, Desplan C (2000). A green fluorescent protein enhancer trap screen in Drosophila photoreceptor cells.  Mechanisms of Development 93, 151-160.

 

Olivia Hatton

Hatton_Headshot

Immunology, virology, and cancer biology of Epstein-Barr virus and its related malignancies; B cell biology.

Selected publications

(* undergraduate student author, § authors contributed equally to this work)

Glanville J§, Huang H§, Nau A, Hatton O, Wagar LE, Rubelt F, Ji X, Han A, Krams SM, Pettus C, Haas N, Lindestram Arlehamn CS, Sette A, Boyd SD, Scriba TJ, Martinez OM, Davis MM.  Identifying Specificity Groups in the T Cell Receptor Repertoire. Nature 547:94 (2017).

Associated News & Views: Reddy ST. The Patterns of T-Cell Target Recognition.  Nature 547:6 (2017).

Hatton O, Strauss-Albee DM, Zhao NQ, Haggadone MD, Pelpola JS*, Krams SM§, Martinez OM§, & Blish CA§.  NKG2A-Expressing Natural Killer Cells Dominate the Response to Autologous Lymphoblastoid Cells Infected with Epstein-Barr Virus.  Frontiers in Immunology 7:607 (2016).

Harris-Arnold A, Arnold CP, Schaffert S, Hatton O, Krams SM, Esquivel CO, & Martinez OM.  EBV Modulates Host Cell microRNA-194 to Promote IL-10 Production and B Lymphoma Survival.  American Journal of Transplantation 15(11):2814 (2015).

Hatton O, Harris-Arnold A, Schaffert S, Krams SM, & Martinez OM.  The Interplay Between Epstein-Barr Virus and B Lymphocytes.  Immunological Research 58(2-3):268 (2014).

Hatton O, Lambert SL, Phillips LK, Vaysberg M, Natkunam Y, Esquivel CO, Krams SM, & Martinez OM.  Syk-Induced Phosphatidylinositol-3-Kinase Activation in Epstein-Barr Virus Post-Transplant Lymphoproliferative Disorder.  American Journal of Transplantation 13(4):833 (2013).

Hatton O§, Lambert SL§, Krams SM, & Martinez OM.  Src Kinase and Syk Activation Initiate PI3K Signaling by a Chimeric Latent Membrane Protein 1 in Epstein-Barr Virus (EBV)+ B Cell Lymphomas.  PLoS One7(8):e42610 (2012).

Hatton O, Martinez OM, & Esquivel CO.  Emerging Therapeutic Strategies for the Treatment of Epstein-Barr Virus (EBV)+ Post-Transplant Lymphoproliferative Disorder (PTLD).  Pediatric Transplantation 16(3):220 (2012).

Hatton O, Phillips LK, Vaysberg M, Hurwich J*, Krams SM, & Martinez OM.  Syk Activation of PI3K/Akt Prevents HtrA2-Dependent Loss of X-linked Inhibitor of Apoptosis Protein (XIAP) to Promote Survival of Epstein-Barr Virus (EBV)+ B Cell Lymphomas.  Journal of Biological Chemistry 286(43):37368 (2011).

Vaysberg M, Hatton O, Lambert SL, Snow AL, Wong B, Krams SM, & Martinez OM.  Tumor-Derived Variants of EBV Latent Membrane Protein 1 Induce Sustained Erk Activation and cFos.  Journal of Biological Chemistry,283(52):36573 (2008).


CHEMISTRY and BIOCHEMISTRY


Margaret DaughertyMargaret Daugherty

In vitro investigation (using thermodynamic and biochemical studies) of (i) issues relating to transcriptional regulation in C. elegans including investigation of MEX-3 interactions with its cognate RNA binding site; MEX-3/MEX-5 interactions; effect of MEX-5 on MEX-3 – RNA interactions, and (ii) issues relating to enzymatic utilization of cyanide as a source of metabolic nitrogen in P. fluorescens.

Selected publications

J.E. Whittington, R.F.Degadillo, T.J. Attebury, L.K. Parkhurst, M.A. Daugherty and L.J. Parkhurst. (2008). TATA-Binding Protein Recognition and Bending of a Consensus Promoter are Protein Species Dependent. Biochemistry, 47, 7264-73.

Mason, A.B., Judson, G.L., Bravo, M.C., Edelstein, A., Byrne, S.L., James, N.G., Roush, E.D. and Fierke, C.A. and Daugherty, M.A.  (2008). Evolution reversed:  The ability to bind iron restored to the N-lobe of murine inhibitor of mouse carbonic anhydrase by strategic mutagenesis. Biochemistry, 4, 9487-95.

Ramsey, J.E., Daugherty, M.A. and Kelm, R.J. (2007). Hydrodynamic Studies on the Quaternary Structure of Recombinant Mouse Purb. Journal of Biological Chemistry, 282, 1552-1560.

Ivancic, M., Spuches, A-M, Guth,E., Daugherty, M.A. Wilcox, D and Lyons B.A. (2005). Backbone Nuclear Relaxation  Characteristics and colorimetric Investigation of the Human Grb7-SH2/erbB2 Peptide Complex. Protein Science, 14, 1556-1569.

 


amydounayAmy Dounay

Selected publications

Chang, C.; Fonseca, K. R.; Li, C.; Horner, W.; Zawadzke, L. E.; Salafia, M. A.; Welch, K. A.; Strick, C. A.; Campbell, B. M.; Gernhardt, S. S.; Rong, H.; Sawant-Basak, A.; Liras, J.; Dounay, A.; Tuttle, J. B.; Verhoest, P.; Maurer, T. S. “Quantitative translational analysis of brain kynurenic acid modulation via irreversible kynurenine aminotransferase II inhibition,” Molecular Pharmacology, 2018, 94, 823-833.

Scott, W.L.; Samaritoni, J.G.;  O’Donnell, M. J.;  Dounay, A.  B.; Fuller, A.A.; Dave, P.S.*; Sanchez, J.M.*;  Tiano, D.G.*; Rivera, D.G. “Ernest Eliel Workshop – US and Cuba Collaboration in Chemistry Education and Neglected Disease Drug Discovery” in Stereochemistry and Global Connectivity: The Legacy of Ernest Eliel, Schmid, D. G.; Maryanoff, C.; Miller, B.; Cheng, H. N., Eds. ACS Publications, 2017.

Pham, T.;* Walden, M.;* Butler, C.; Diaz-Gonzalez, R.; Pérez-Moreno, G.; Ceballos-Pérez, G.; Gomez-Pérez, V.; García-Hernández, R.; Zecca, H.;* Krakoff, E.;* Kopec, B.;* Ichire, O.; Mackenzie, C.;* Pitot, M.;* Ruiz, L.M.; Gamarro, F.; González-Pacanowska, D.; Navarro, M.;Dounay, A. B. “Novel 1,2-dihydroquinazolin-2ones: Design, synthesis, and biological evaluation against Trypanosoma brucei,” Bioorg. Med. Chem. Lett. 2017, 27, 3629-3635.

Ichire, O.; Jans, P.*; Parfenov, G.*; Dounay, A. B. “A Safe and Selective Method for Reduction of 2-Nitrophenylacetic Acid Systems to N-Aryl Hydroxamic Acids Using Continuous Flow Hydrogenation,” Tetrahedron Lett. 2017, 58, 582-585.

Dounay, A. B.; Driscoll, L. L.; Blessing, P. M.*; Comfort, H. M.;* Mares, J. M.* “Agony and Ecstasy: Party Drug or Breakthrough Treatment for PTSD,” National Center for Case Study Teaching in Science, [Online] 2017, http://sciencecases.lib.buffalo.edu/cs/files/mdma.pdf.

Dounay, A. B.; Tuttle, J. B.; Verhoest, P. R. “Challenges and Opportunities in the Discovery of New Therapeutics Targeting the Kynurenine Pathway” J. Med. Chem. 2015, 58, 8762-8782.

Dounay, A. B. “Telaprevir (Incivek) and Boceprevir (Victrelis): NS3/4A Inhibitors for Treatment for Hepatitis C Virus (HCV).” in Innovative Drug Synthesis, Li, J. J.; Johnson, D. S., Eds.: Wiley, New York, 2015.

Kozak, R.; Campbell, B.; Strick, C.; Horner, W.; Hoffmann, W.; Kiss, T.; Chapin, D.; McGinnis, D. Abbott, A.; Roberts, B.; Fonseca, K.; Guanowsky, V.; Young, D.; Seymour, P.; Dounay, A.; Hajos, M.; William, G.; Castner, S. A. "Reduction of Kynurenic Acid Improves Cognitive Function," J. Neurosci. 2014, 34, 10592-10602.

Dounay, A. B.; Anderson, M.; Bechle, B. M.; Evrard, E.; Gan, X.; Kim, J.-Y.; McAllister, L. A.; Pandit, J.; Rong, S.; Salafia, M. A.; Tuttle, J. B.; Zawadzke, L. E.; Verhoest, P. R. “PF-​04859989 as a template for structure-​based drug design: Identification of new pyrazole series of irreversible KAT II inhibitors with improved lipophilic efficiency” Bioorg. Med. Chem. Lett. 2013, 23, 1961.

Dounay, A. B.; Curran, T. “Imidazoles and Benzimidazoles.” In Heterocyclic Chemistry in Drug Discovery, Li, J. J., Ed.; Wiley, New York, 2013.

Henderson, J. L.; Sawant-Basak, A.; Tuttle, J. B.; Dounay, A. B; McAllister, L. A.; Pandit, J.; Rong, S.; Hou, X.; Bechle, B. M.; Kim, J. –Y.; Parikh, V.; Ghosh, S.; Evrard, E.; Zawadzke, L. E.; Salafia, M. A.; Rago, B.; Obach, R. S.; Clark, A.; Fonseca, K. R.; Cheng, C.; Verhoest, P. R.; “Discovery of Hydroxamate Bioisosteres as KAT II Inhibitors with Improved Bioavailability and Pharmacokinetics,” MedChemComm 2013, 4, 125.

Tuttle, J. B.; Anderson, M.; Bechle, B. M.; Campbell, B. M.; Chang, C.; Dounay, A. B.; Evrard, E.; Fonseca, K. R.; Gan, X.; Ghosh, S.; Horner, W.; James, L. C.; Kim, J. –Y.; McAllister, L. A.; Pandit, J.; Parikh, V. D.; Rago, B. J.; Salafia, M. A.; Strick, C. A.; Zawadzke, L. E.; Verhoest, P. R. “Structure-Based Design of Irreversible Human KAT II Inhibitors: Discovery of New Potency-Enhancing Interactions” ACS Med. Chem. Lett. 2013, 4, 37.

Li, C. S. –W.; Zhang, L.; Haske, T.; Dounay, A.; Gray, D.; Barta, N.; Brodfuehrer, J.; Lepsy, C.; Campbell, B. “Mechanism-Based Pharmacokinetic/ Pharmacodynamic Modeling of Rat Prefrontal Cortical Dopamine Response to Dual Acting Norepinephrine Reuptake Inhibitor and 5-HT1A Partial Agonist” Am. Assoc. Pharm. Sci. J. 2012, 14, 365.

Dounay, A. B.; Bechle, B. M.; Campbell, B. M.; Claffey, M. M.; Gan, X.; Hayward, M. M.; Kim, J. -Y.; Rong, S.; Salafia, M.; Tuttle, J. B.; Verhoest, P. R. “Discovery of brain-penetrant, irreversible kynurenine aminotransferase II inhibitors for schizophrenia” ACS Med. Chem. Lett. 2012, 3, 187.