While the advent of the fraternity system at Colorado College can be located almost directly in the College's reluctance to build male dormitories in the beginning of the century, the sororities came to be through a different process altogether. In 1930, The Colorado College was looking to make some profound changes. The College brought in two outside consultants to evaluate the academic program, and to recommend changes and improvements. While the main impetus of the new program was to divide academics into three main schools (School of Letters and Fine Arts, School of Social Sciences, and the School of Natural Sciences), the consultants also advocated a revision of social life at CC.

Upon their recommendation, Colorado College granted sorority status to the four female literary societies. The Minerva society became Delta Gamma, Contemporary became Kappa Alpha Theta, Hypatia became Kappa Kappa Gamma, and Zelathian became Gamma Phi Beta (now defunct). Finally, women were not allowed to live in their sorority houses. Basically, the sorority lodges served as a meeting place for social and intellectual interaction.

From 1985 to 1995, participation in Greek Life at CC dropped from 30% of the student body to only 15%. Nationally and locally, Greek Life was criticized for its reliance on alcohol use and abuse. Strategic Planning in the 90s, by then President of the College Kathryn Mohrman, almost led to the abolition of the sororities and fraternities on the campus. Instead of revoking the Greek chapters, Mohrman relocated the Greek quad to East Campus. While Kappa Alpha Theta and Kappa Kappa Gamma opted to relocate their lodges, Delta Gamma decided to build a new lodge on the East campus site. In 1995, a low house total and unsuccessful rush led to the voluntary dissolution of Gamma Phi Beta. Renewed interest in the Colorado College Panhellenic sororities at Colorado College has strengthened the three remaining chapters.

Greek Life continues to evolve at Colorado College, providing philanthropic involovement, leadership and social opportunities, and strong sisterhood for its many members.